VIP papers

Papers authored/coauthored by the VIP-network and from the VIP1, VIP2 and COVIP studies.




Provision of critical care for the elderly in Europe: a retrospective comparison of national healthcare frameworks in intensive care units

Wernly B, Beil M, Bruno RR, Binnebössel S, Kelm M, Sigal S, van Heerden PV, Boumendil A, Artigas A, Cecconi M, Marsh B, Moreno R, Oeyen S, Bollen Pinto B, Szczeklik W, Leaver S, Walther SM, Schefold JC, Joannidis M, Fjølner J, Zafeiridis T, de Lange D, Guidet B, Flaatten H, Jung C; VIP2 study group
British Medical Journal Open. 2021-06-03
PubmedFree full text linkVIP1VIP2

Frailty and survival in elderly intensive care patients in Norway

Andersen FH, Ariansen Haaland Ø, Klepstad P, Flaatten H
Acta Anaesthesiol Scand. 2021-04-25
PubmedFree full text linkVIP2

The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study

Jung C, Flaatten H, Fjølner J, Bruno RR, Wernly B, Artigas A, Bollen Pinto B, Schefold JC, Wolff G, Kelm M, Beil M, Sviri S, van Heerden PV, Szczeklik W, Czuczwar M, Elhadi M, Joannidis M, Oeyen S, Zafeiridis T, Marsh B, Andersen FH, Moreno R, Cecconi M, Leaver S, Boumendil A, De Lange DW, Guidet B; COVIP study group.
Critical Care. 2021-04-20;Apr 19;149
PubmedFree full text linkCOVIP

Frailty is associated with long-term outcome in patients with sepsis who are over 80 years old: results from an observational study in 241 European ICUs

Haas LEM, Boumendil A, Flaatten H, Guidet B, Ibarz M, Jung C, Moreno R, Morandi A, Andersen FH, Zafeiridis T, Walther S, Oeyen S, Leaver S, Watson X, Boulanger C, Szczeklik W, Schefold JC, Cecconi M, Marsh B, Joannidis M, Nalapko Y, Elhadi M, Fjølner J, Artigas A, de Lange DW; VIP2 study group
Age and ageing. 2021-03-23
PubmedVIP2

Reliability of the Clinical Frailty Scale in very elderly ICU patients: a prospective European study

Flaatten H, Guidet B, Andersen FH, Artigas A, Cecconi M, Boumendil A, Elhadi M, Fjølner J, Joannidis M, Jung C, Leaver S, Marsh B, Moreno R, Oeyen S, Nalapko Y, Schefold JC, Szczeklik W, Walther S, Watson X, Zafeiridis T, de Lange DW
Annals of intensive care. 2021-02-03;11
PubmedFree full text linkVIP2

Frailty as a Prognostic Indicator in Intensive Care

Jung C, Bruno RR, Wernly B, Wolff G, Beil M, Kelm M
Deutsches Ärzteblatt international. 2021-01-04;117;668-673
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Sex-specific outcome disparities in very old patients admitted to intensive care medicine: a propensity matched analysis

Wernly B, Bruno RR, Kelm M, Boumendil A, Morandi A, Andersen FH, Artigas A, Finazzi S, Cecconi M, Christensen S, Faraldi L, Lichtenauer M, Muessig JM, Marsh B, Moreno R, Oeyen S, Öhman CA, Pinto BB, Soliman IW, Szczeklik W, Niederseer D, Valentin A, Watson X, Leaver S, Boulanger C, Walther S, Schefold JC, Joannidis M, Nalapko Y, Elhadi M, Fjølner J, Zafeiridis T, De Lange DW, Guidet B, Flaatten H, Jung C; VIP2 Study Group.
Scientific reports. 2020-11-01;10
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The wave of very old people in the intensive care unit-A challenge in decision-making

van Heerden PV, Sviri S, Beil M, Szczeklik W, de Lange D, Jung C, Guidet B, Leaver S, Rhodes A, Boumendil A, Flaatten H
J Crit Care. 2020-09-10;Sep 10;290-293
Pubmed

Prognostication in older ICU patients: mission impossible?

Flaatten H, Beil M, Guidet B
Br J Anaesth. 2020-08-14;125;655-657
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Therapy limitation in octogenarians in German intensive care units is associated with a longer length of stay and increased 30 days mortality: A prospective multicenter study

Bruno RR, Wernly B, Beil M, Muessig JM, Rahmel T, Graf T, Meybohm P, Schaller SJ, Allgäuer S, Franz M, Westphal JG, Barth E, Ebelt H, Fuest K, Horacek M, Schuster M, Dubler S, Schering S, Wolff G, Steiner S, Rabe C, Dieck T, Lauten A, Sacher AL, Brenner T, Bloos F, Jánosi RA, Simon P, Utzolino S, Kelm M, De Lange DW, Guidet B, Flaatten H, Jung C
J Crit Care. 2020-08-01;60;58-63
PubmedVIP1VIP2

Elderly Patients in the Intensive Care Unit

Flaatten H, Beil M, Guidet B
Semin Respir Crit Care Med. 2020-08-01;17(01)
Pubmed

Inhibitors of the Renin-Angiotensin-Aldosterone System and Covid-19 in critically ill elderly patients

Jung C, Bruno RR, Wernly B, Joannidis M, Oeyen S, Zafeiridis T, Marsh B, Andersen FH, Moreno R, Fernandes AM, Artigas A, Pinto BB, Schefold J, Wolff G, Kelm M, De Lange DW, Guidet B, Flaatten H, Fjølner J
European heart journal. Cardiovascular pharmacotherapy. 2020-07-09;Jul 9
PubmedCOVIP

The good, the bad and the ugly: pandemic priority decisions and triage

Flaatten H, Van Heerden V, Jung C, Beil M, Leaver S, Rhodes A, Guidet B, deLange DW
Journal of Medical Ethics. 2020-06-10
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Sepsis at ICU Admission Does Not Decrease 30-day Survival in Very Old Patients: A Post-Hoc Analysis of the VIP1 Multinational Cohort Study

Ibarz M, Boumendil A, Haas LEM, Irazabal M, Flaatten H, de Lange DW, Morandi A, Andersen FH, Bertolini G, Cecconi M, Christensen S, Faraldi L, Fjølner J, Jung C, Marsh B, Moreno R, Oeyen S, Öhman CA, Bollen Pinto B, Soliman IW, Szczeklik W, Valentin A, Watson X, Zaferidis T, Guidet B, Artigas A; VIP1 study
Annals of intensive care. 2020-05-13;10
PubmedVIP1

The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study. Intensive care medicine

Guidet B, de Lange DW, Boumendil A, Leaver S, Watson X, Boulanger C, Szczeklik W, Artigas A, Morandi A, Andersen F), Zafeiridis T), Jung C), Moreno R), Walther S, Oeyen S, Schefold JC, Cecconi M, Marsh B, Joannidis M, Nalapko Y, Elhadi M, Fjølner J, Flaatten H; VIP2 study group.
Intensive Care Medicine. 2019-11-29;46;57-69
PubmedFree full text linkVIP2

Validation of the clinical frailty score (CFS) in French language

Abraham P, Courvoisier DS, Annweiler C, Lenoir C, Millien T, Dalmaz F, Flaatten H, Moreno R, Christensen S, de Lange DW, Guidet B, Bendjelid K, Walder B, Bollen Pinto B
BMC Geriatr. 2019-11-21;19;322
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Frailty increases mortality among patients ≥80 years old treated in Polish ICUs

Fronczek J, Polok KJ, Nowak-Kózka I, Włudarczyk A, Górka J, Czuczwar M, Krawczyk P, Ziętkiewicz M, Nowak ŁR, Żukowski M, Kotfis K, Cwyl K, Gajdosz R, Bohatyrewicz R, Biernawska J, Grudzień P, Nasiłowski P, Popek N, Cyrankiewicz W, Wawrzyniak K, Wnuk M, Maciejewski D, Studzińska D, Bernas S, Piechota M, Machała W, Serwa M, Wujtewicz M, Stefaniak J, Szymkowiak M, Gawda R, Adamik B, Kozera N, Goździk W, Flaatten H, Szczeklik W
Anaesthesiology Intensive Therapy. 2019-10-11;50
PubmedFree full text linkVIP1

The hospital frailty risk score is of limited value in intensive care unit patients

Bruno RR, Wernly B, Flaatten H, Schölzel F, Kelm M, Jung C
Critical Care. 2019-07-02;23;239
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Huge variation in obtaining ethical permission for a non-interventional observational study in Europe

de Lange DW, Guidet B, Andersen FH, Artigas A, Bertolini G, Moreno R, Christensen S, Cecconi M, Agvald-Ohman C, Gradisek P, Jung C, Marsh BJ, Oeyen S, Bollen Pinto B, Szczeklik W, Watson X, Zafeiridis T, Flaatten H
BMC Medical Ethics. 2019-06-03;20
PubmedFree full text linkVIP1

A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention

Jung C, Wernly B, Muessig JM, Kelm M, Boumendil A, Morandi A, Andersen FH, Artigas A, Bertolini G, Cecconi M, Christensen S, Faraldi L, Fjølner J, Lichtenauer M, Bruno RR, Marsh B, Moreno R, Oeyen S, Öhman CA, Pinto BB, Soliman IW, Szczeklik W, Valentin A, Watson X, Zafeiridis T, De Lange DW, Guidet B, Flaatten H; VIP1 study group
J Crit Care. 2019-05-02;52;141-148
PubmedVIP1

Cumulative Prognostic Score Predicting Mortality in Patients Older Than 80 Years Admitted to the ICU

de Lange DW, Brinkman S, Flaatten H, Boumendil A, Morandi A, Andersen FH, Artigas A, Bertolini G, Cecconi M, Christensen S, Faraldi L, Fjølner J, Jung C, Marsh B, Moreno R, Oeyen S, Öhman CA, Bollen Pinto B, de Smet AMGA, Soliman IW, Szczeklik W, Valentin A, Watson X, Zafeiridis T, Guidet B; VIP1 Study Group
Journal of the American Geriatrics Society. 2019-04-12;67;1263-1267
PubmedVIP1

How Does Frailty Affect ICU Outcome?

Hans Flaatten, Christian Jung, Helene Vallet, Bertrand Guidet
Current Anesthesiology Reports . 2019-04-01;144-150

Caring for the Critically Ill Patients over 80: A Narrative Review

Guidet, Bertrand, Helene Vallet, Jacques Boddaert, Dylan W. de Lange, Alessandro Morandi, Guillaume Leblanc, Antonio Artigas, and Hans Flaatten
Annals of Intensive Care. 2018-11-26
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Frailty: We need valid and reliable tools in critical care

Flaatten H, Clegg A
Intensive Care Medicine. 2018-11-01;44;1973‐1975
Pubmed

Frailty Is Associated With an Increased Mortality Among Patients ≥ 80 Years Old Treated in Polish ICUs

Jakub Fronczek, Kamil Jurand Polok, Ilona Nowak-Kózka, Anna Włudarczyk, Jacek Górka, Mirosław Czuczwar, Paweł Krawczyk, Mirosław Ziętkiewicz, Łukasz R Nowak, Maciej Żukowski, Katarzyna Kotfis, Katarzyna Cwyl, Ryszard Gajdosz, Romuald Bohatyrewicz, Jowita Biernawska, Paweł Grudzień, Paweł Nasiłowski, Natalia Popek, Waldemar Cyrankiewicz, Katarzyna Wawrzyniak, Marek Wnuk, Dariusz Maciejewski, Dorota Studzińska, Szymon Bernas, Mariusz Piechota, Waldemar Machała, Marta Serwa, Maria Wujtewicz, Jan Stefaniak, Małgorzata Szymkowiak, Ryszard Gawda, Barbara Adamik, Natalia Kozera, Waldemar Goździk, Hans Flaatten, Wojciech Szczeklik
Anaesthesiology intensive therapy / Anestezjologia intensywna terapia . 2018-09-22;50;245-251
PubmedVIP1

Clinical Frailty Scale (CFS) reliably stratifies octogenarians in German ICUs: a multicentre prospective cohort study

Muessig JM, Nia AM, Masyuk M, Lauten A, Sacher AL, Brenner T, Franz M, Bloos F, Ebelt H, Schaller SJ, Fuest K, Rabe C, Dieck T, Steiner S, Graf T, Jánosi RA, Meybohm P, Simon P, Utzolino S, Rahmel T, Barth E, Schuster M, Kelm M, Jung C.
BMC Geriatrics. 2018-07-13;18;162
PubmedFree full text linkVIP1

Predicting outcomes in very old ICU patients: time to focus on the past?

Flaatten H, Oeyen S, deLange DW
Intensive Care Medicine. 2018-07-02;44;1344-1345
Pubmed

Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit

Guidet B, Flaatten H, Boumendil A, Morandi A, Andersen FH, Artigas A, Bertolini G, Cecconi M, Christensen S, Faraldi L, Fjølner J, Jung C, Marsh B, Moreno R, Oeyen S, Öhman CA, Pinto BB, Soliman IW, Szczeklik W, Valentin A, Watson X, Zafeiridis T, De Lange DW; VIP1 study group
Intensive Care Medicine. 2018-05-17;44;1027-1038
PubmedFree full text linkVIP1

Should this elderly patient be admitted to the ICU?

Guidet B, de Lange DW, Flaatten H
Intensive Care Medicine. 2018-01-22;44;1926-1928
Pubmed

The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years)

Flaatten H, De Lange DW, Morandi A, Andersen FH, Artigas A, Bertolini G, Boumendil A, Cecconi M, Christensen S, Faraldi L, Fjølner J, Jung C, Marsh B, Moreno R, Oeyen S, Öhman CA, Pinto BB, Soliman IW, Szczeklik W, Valentin A, Watson X, Zaferidis T, Guidet B; VIP1 study group
Intensive Care Medicine. 2017-09-21;43;1820-1828
PubmedVIP1

The Status of Intensive Care Medicine Research and a Future Agenda for Very Old Patients in the ICU

Moreno R, Christensen S, Joynt GM, Bagshaw SM, Sprung CL, Benoit D, Soares M, Guidet B
Intensive Care Medicine. 2017-09-01;43;1319-1328
Pubmed